Withdrawal signs or symptoms can happen in breastfed infants when maternal administration of an opioid analgesic is stopped, or when breastfeeding is stopped.

Patients should know that this drug, even when taken as proposed may result in habit, abuse, and misuse; instruct patients never to share their drug with Some others and defend their drug from theft or misuse.

Nursing Mothers At the very least a single Demise was described inside of a nursing infant who was subjected to high amounts of morphine in breast milk because the mother was an extremely-swift metabolizer of codeine. Breastfeeding just isn't proposed throughout treatment with acetaminophen and codeine phosphate tablets.

Addiction, Abuse, and Misuse Because the utilization of acetaminophen and codeine phosphate tablets expose clients and other customers for the pitfalls of opioid dependancy, abuse, and misuse, which can result in overdose and Demise, evaluate Each individual patient’s danger just before prescribing and reassess all clients consistently for the event of such behaviors and situations (see WARNINGS).

Individuals needs to be educated with regard to the symptoms of serious skin reactions, and use in the drug really should be discontinued at the main look of skin rash or some other indication of hypersensitivity.

Opioids cross the placenta and may create respiratory despair and psycho-physiologic outcomes in neonates. An opioid antagonist, like naloxone, have to be available for reversal of opioid-induced respiratory despair within the neonate. Acetaminophen and codeine phosphate tablets are usually not advised for use in Expecting Females during or quickly before labor, when other analgesic strategies tend to be more acceptable.

Neonatal Opioid Withdrawal Syndrome Notify woman patients of reproductive prospective that utilization of acetaminophen and codeine phosphate tablets for an prolonged time period through pregnancy can result in neonatal opioid withdrawal syndrome, which may be lifestyle-threatening if not identified and dealt with (see Safety measures, Pregnancy).

Discontinuation/reduction designs must be individualized and consider into account numerous elements which include kind of agony, dose and length of treatment method, and affected person unique Bodily and psychological characteristics; sufferers should obtain ongoing care and abide by-up that addresses agreed upon get more info and reasonable aims.

People ought to recognize this drug has likely significant Unintended effects such as adrenal insufficiency, significant constipation, and hypotension, and potentially considerable drug interactions, In particular with other CNS depressants, which include alcohol; sufferers really should be instructed to talk to a healthcare Skilled if any new signs or symptoms or Negative effects come about.

 Instruct people never to share acetaminophen and codeine phosphate tablets with Some others and also to consider ways to website shield acetaminophen and codeine phosphate tablets from theft or misuse.

Even though it helps Lots of people, this medication might occasionally trigger read more addiction. This risk may be bigger When you've got a compound click here use disorder (which include overuse of or habit to prescription read more drugs/Alcoholic beverages).

Instruct sufferers to discontinue acetaminophen and codeine phosphate tablets immediately and search for health-related care whenever they expertise these signs. Do not prescribe acetaminophen and codeine phosphate tablets for clients with acetaminophen allergy (see Safeguards, Information for Clients/Caregivers).

Evaluate clients receiving acetaminophen and codeine phosphate tablets and any CYP3A4 inhibitor or inducer for symptoms and symptoms that will mirror opioid toxicity and opioid withdrawal when acetaminophen and codeine phosphate tablets are utilised along side inhibitors and inducers of CYP3A4 (see PRECAUTIONS, Drug Interactions).

Other ache relievers (including naproxen, ibuprofen) may additionally be prescribed using this medication. Question your health practitioner or pharmacist about working with this products properly with other prescription drugs.